Publications

Publications by David Weis in PubMed

  1. Komar-Panicucci, S;  Weis, D;  Bakker, G;  Qiao, T;  Sherman, F; McLendon, G. Thermodynamics of the equilibrium unfolding of oxidized and reduced Saccharomyces cerevisiae iso-1-cytochromes c. Biochemistry 1994, 33, 10556-10560.
  2. Weis, D D; Ewing, G E. Infrared spectroscopic signatures of (NH4)2SO4 aerosols. J Geophys Res 1996, 101, 18709-18720.
  3. Weis, D D; Ewing, G E. Infrared spectroscopy of tropospheric aerosols. Bull Chem Technol Macedonia 1997, 16, 3-10.
  4. Weis, D D; Ewing, G E. Absorption anomalies in ratio and subtraction FT-IR spectroscopy. Anal Chem 1998, 70, 3175-3183.
  5. Weis, D D; Ewing, G E. The reaction of nitrogen dioxide with sea salt aerosol. J Phys Chem A 1999, 103, 4865-4873.
  6. Weis, D D; Ewing, G E. Water content and morphology of sodium chloride aerosol particles. J Geophys Res 1999, 104, 21275-21285.
  7. Weis, D D; Nardozzi, J D. Enzyme kinetics in acoustically levitated droplets of supercooled water: a novel approach to cryoenzymology. Anal Chem 2005, 77, 2558-2563.
  8. Weis, D D;  Engen, J R; Kass, I J. Semi-automated data processing of hydrogen exchange mass spectra using HX-Express. J Amer Soc Mass Spectrom 2006, 17, 1700-1703.
  9. Weis, D D;  Kjellen, P;  Sefton, B M; Engen, J R. Altered dynamics in Lck SH3 upon binding to the LBD1 domain of Herpesvirus saimiri Tip. Protein Sci 2006, 15, 2402-2410.
  10. Weis, D D;  Wales, T E;  Engen, J R;  Hotchko, M; Ten Eyck, L F. Identification and characterization of EX1 kinetics in H/D exchange mass spectrometry by peak width analysis. J Amer Soc Mass Spectrom 2006, 17, 1498-1509.
  11. Mitchell, J L;  Trible, R P;  Emert-Sedlak, L A;  Weis, D D;  Lerner, E C;  Applen, J J;  Sefton, B M;  Smithgall, T E; Engen, J R. Functional characterization and conformational analysis of the Herpesvirus saimiri Tip-C484 protein. J Mol Biol 2007, 366, 1282-1293.
  12. Rathinavelan, T;  Zhang, L L;  Picking, W L;  Weis, D D;  De Guzman, R N; Im, W. A repulsive electrostatic mechanism for protein export through the type III secretion apparatus. Biophys J 2010, 98, 452-461.
  13. T. R. Keppel, M. E. Jacques, D. D. Weis, The use of acetone as a substitute for acetonitrile in analysis of peptides by liquid chromatography/electrospray ionization mass spectrometry. Rapid Commun Mass Spectrom 2010, 24, 6-10.
  14.  Keppel, T R;  Howard, B A; Weis, D D. Mapping unstructured regions and synergistic folding in intrinsically disordered proteins with amide H/D exchange mass spectrometry. Biochemistry 2011, 50, 8722-8732.
  15. Keppel, T R;  Jacques, M E;  Young, R W;  Ratzlaff, K L; Weis, D D. An efficient and inexpensive refrigerated LC system for H/D exchange mass spectrometry. J Am Soc Mass Spectrom 2011, 22, 1472-1476.
  16. Majumdar, R;  Manikwar, P;  Hickey, J M;  Arora, J;  Middaugh, C R;  Volkin, D B; Weis, D D. Minimizing carry-over in an online pepsin digestion system used for the H/D exchange mass spectrometric analysis of an IgG1 monoclonal antibody. J Am Soc Mass Spectrom 2012, 23, 2140-2148.
  17. Rumi-Masante, J;  Rusinga, F I;  Lester, T E;  Dunlap, T B;  Williams, T D;  Dunker, A K;  Weis, D D; Creamer, T P. Structural basis for activation of calcineurin by calmodulin. J Mol Biol 2012, 415, 307-317.
  18. Engen, J R;  Wales, T E;  Chen, S;  Marzluff, E M;  Hassell, K M;  Weis, D D; Smithgall, T E. Partial cooperative unfolding in proteins as observed by hydrogen exchange mass spectrometry. Int Rev Phys Chem 2013, 32, 96-127.
  19. Keppel, T R; Weis, D D. Analysis of disordered proteins using a simple apparatus for millisecond quench-flow H/D exchange. Anal Chem 2013, 85, 5161-5168.
  20. Majumdar, R;  Manikwar, P;  Hickey, J M;  Samra, H S;  Sathish, H A;  Bishop, S M;  Middaugh, C R;  Volkin, D B; Weis, D D. Effects of salts from the Hofmeister series on the conformational stability, aggregation propensity, and local flexibility of an IgG1 monoclonal antibody. Biochemistry 2013, 52, 3376–3389.
  21. Manikwar, P;  Majumdar, R;  Hickey, J M;  Thakkar, S V;  Samra, H S;  Sathish, H A;  Bishop, S M;  Middaugh, C R;  Weis, D D; Volkin, D B. Correlating excipient effects on conformational and storage stability of an IgG1 monoclonal antibody with local dynamics as measured by hydrogen/deuterium-exchange mass spectrometry. J Pharm Sci 2013, 102, 2136-2151.
  22. M. Guttman, D. D. Weis, J. R. Engen, K. K. Lee, Analysis of overlapped and noisy hydrogen/deuterium exchange mass spectra. J Am Soc Mass Spectrom 2013, 24, 1906-12.
  23. M. A. Alsenaidy, J. H. Kim, R. Majumdar, D. D. Weis, S. B. Joshi, T. J. Tolbert, C. R. Middaugh, D. B. Volkin, High-Throughput Biophysical Analysis and Data Visualization of Conformational Stability of an IgG1 Monoclonal Antibody After Deglycosylation. J Pharm Sci 2013, 102, 3942-3956.
  24. Y. Xia, N. DiPrimio, T. R. Keppel, B. Vo, K. Fraser, K. P. Battaile, C. W. Egan, C. Bystroff, S. W. Lovell, D. D. Weis, J. C. Anderson, J. Karanicolas, The designability of protein switches by chemical rescue of structure: mechanisms of inactivation and reactivation. J Amer Chem Soc accepted.

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