HX-Express is Microsoft Excel-based software for semi-automated analysis of hydrogen exchange mass spectrometry data. Any data in (x,y) format can be analyzed or spectral data can be directly imported from Waters Masslynx software. Output is deuterium uptake curves and peak-width plots.
The beta version of the software requires Microsoft Excel 2003. An Excel 2007-compatible version is currently under development.
Modification of the software is highly encouraged. If you have developed useful modifications in-house that you think would be useful to the wider community, please contact David Weis at firstname.lastname@example.org. You are also welcome to redistribute the program or distribute modified versions subject to the terms of the software license.
Described in the publication:
Weis, D. D., Engen, J. R., Kass, I. J. (2006). Semi-automated analysis of hydrogen exchange mass spectra using HX-Express. J. Amer. Soc. Mass Spectrom. 17(12), 1700-1703. DOI:10.1016/j.jasms.2006.07.025.
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Excel Peptide Functions Add-In
This Excel Add-In creates two new Excel functions.
- PEPMASS will return the monoisotopic or average mass of an amino acid sequence.
- PEPFORM will return the chemical formula of an amino acid sequence.
Both functions recognize the standard 20, one-letter amino acid codes in either lowercase or uppercase. Spaces are tolerated, but any other characters will return a worksheet error (#NAME?).
These functions have been tested on Excel 2010 in Windows 7. They are expected to work in Excel 2007 as well.
This software is free under the terms of the GNU General Public License (GPL). Please cite the above reference in any resulting publications. Read the FAQ and help screens within the software before contacting the Author with questions or before reporting bugs.
Software copyright 2011, David D. Weis, Ph.D.